CAMK2G/CAMK2B Antibody - Cat. #: CSB-PA181746

SKU: CSB-PA181746

Size :100ul

Clone Number:

Aliases:Calcium/calmodulin-dependent protein kinase type II gamma chain; EC 2.7.11.17; CaM-kinase II gamma chain; CaM kinase II subunit gamma; CaMK-II subunit gamma

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13555/Q13554

Immunogen:Synthesized peptide derived from C-terminal of Human CaMK2?/γ.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.Deloukas P., Nature 429:375-381(2004).Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997).Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CAMK2G/CAMK2B

Research Areas:Neuroscience;Signal transduction