Calnexin Rabbit pAb

SKU: EA214

Size: 100μL

Source:Rabbit

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-2,000 IHC 1:200-500

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):75,80,90kDa

Human_gene_id:821

Human_swiss_prot_no:P27824

Subcellular_location:Endoplasmic reticulum membrane,Melanosome.

Other_name:CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody

Background:Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.