Bovine Thioredoxin Reductase 1, TXNRD1 ELISA Kit

SKU: E2252Bo

Size:96 Tests-1 Kit

Background:Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:TXNRD1

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.057mU/mL

Detection range:0.1-40mU/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Thioredoxin reductase 1

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O62768

MASS(Da):54,770

GeneID:282388

Synonyms:Thioredoxin reductase 1, cytoplasmic;Thioredoxin reductase TR1;TR;TXNRD1

Gene names:TXNRD1

Standard solution:48mU/mL