Bovine Hyaluronan synthase 2,HAS2 ELISA KIT

SKU: E0124Bo

Size:96Tests

Background:Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:HAS2

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:1.24ng/ml

Detection range:2.5-160ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Hyaluronan synthase 2

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O97711

MASS(Da):63459

GeneID:281220

Synonyms:HAS2

Gene names:HAS2

Standard solution:320ng/ml