Bovine 6-phosphofructokinase,liver type,PFKL ELISA KIT

SKU: E0153Bo

Size:96Tests

Background:Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (By similarity). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity). {ECO:0000250|UniProtKB:P12382, ECO:0000255|HAMAP-Rule:MF_03184}.

Research_area:

Applications:ELISA

Target_protein:PFKL

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.25ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:6-phosphofructokinase,liver type

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:A1A4J1

MASS(Da):85292

GeneID:508683

Synonyms:PFKL

Gene names:PFKL

Standard solution:64ng/ml