BMP4 Monoclonal Antibody

SKU: BT-MCA3394

Size:100μL

Background:The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Research_area:Cancer, Stem cells, Cardiovascular, Signal transduction, Developmental biology

Target_protein:BMP4

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:10F4B4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:BMP4

Immunogen:Purified recombinant fragment of human BMP4 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):64kDa

UniProt accession:P12644

Synonyms:ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, BMP4

GeneID:652