Bmi-1 (F270)Rabbit pAb

SKU: EA363

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human

Dilution:WB 1:1,000-2,000

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):37-43kDa

Human_gene_id:100532731

Human_swiss_prot_no:P35226

Subcellular_location:Cytoplasm, Nucleus

Other_name:PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51

Background:Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells .