BD1L1 rabbit pAb

SKU: ES10054

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human protein . at AA range: 1280-1360

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):335kD

Human_gene_id:259282

Human_swiss_prot_no:Q8NFC6

Subcellular_location:Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .

Other_name:

Background:Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.