BAG2 Polyclonal Antibody

SKU: E-AB-19397

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BAG2

Target Synonym: BAG 2;BAG family molecular chaperone regulator 2;BAG-2;BAG-family molecular chaperone regulator-2;Bag2;BAG2;BCL 2 associated athanogene 2;Bcl-2-associated athanogene 2;BCL2 associated athanogene 2;BCL2-associated athanogene 2;dJ417I1.2 (BAG family molecular chaperone regulator 2);dJ417I1.2;KIAA0576;MGC149462;OTTHUMP00000016668

Research Areas: Cell Biology;Signal Transduction;Cancer;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O95816

Accession:

Background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human BAG2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:30-1:150

Calculated MW: 24 kDa

ObservedMW: Refer to figures