BACE1 antibody , Cat. # FNab10412

SKU: FNab10412

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Immunogen:beta-site APP-cleaving enzyme 1

Synonyms:BACE, KIAA1149

Observed MW:50-55 kDa

Uniprot ID:P56817

Reactivity:Human, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID:23621

Research Area:Neuroscience, Metabolism