AUP1 Antibody - Cat. #: CSB-PA258902

SKU: CSB-PA258902

Size :50ul

Clone Number:

Aliases:AA589454 antibody; Ancient ubiquitous protein 1 antibody; AUP 1 antibody; aup1 antibody; AUP1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y679

Immunogen:Fusion protein of Human AUP1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AUP1

Research Areas:Cardiovascular?Cell biology;Metabolism