ASH2L Polyclonal Antibody

SKU: E-AB-10964

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ASH2L

Target Synonym:ASH 2;Ash2 (absent small or homeotic) like;Ash2 (absent;small;or homeotic) like (Drosophila);ASH2;ASH2 LIKE;ASH2 like protein;ASH2-like protein;Ash2l;ASH2L;ASH2L1>;ASH2L2;Bre 2;Bre2;Discs 2-like;Drosophila absent;small;or homeotic;Drosophila ASH2-like;Set1/Ash2 histone methyltransferase complex subunit ASH2

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9UBL3

Accession:

Background:The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.

Concentration:0.4 mg/mL

Immunogen:Recombinant protein of human ASH2L

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: