ARL6IP1 Antibody - Cat. #: CSB-PA178890

SKU: CSB-PA178890

Size :50ul

Clone Number:

Aliases:ADP ribosylation factor like 6 interacting protein antibody; ADP-ribosylation factor-like protein 6-interacting protein 1 antibody; Aip-1 antibody; Aip1 antibody; AR6P1_HUMAN antibody; ARL-6-interacting protein 1 antibody; ARL6 interacting protein 1 antibody; ARL6IP antibody; Arl6ip1 antibody; ARMER antibody; KIAA0069 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15041

Immunogen:Fusion protein of Human ARL6IP1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ARL6IP1

Research Areas:Cell biology