Anti-UBXN8 Antibody Picoband®

SKU: A13427-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: UBXN8

Specificity:

Background: p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human UBXN8 recombinant protein (Position: N149-N270).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Yamabe, Y., Ichikawa, K., Sugawara, K., Imamura, O., Shimamoto, A., Suzuki, N., Tokutake, Y., Goto, M., Sugawara, M., Furuichi, Y. Cloning and characterization of Rep-8 (D8S2298E) in the human chromosome 8p11.2-p12. Genomics 39: 198-204, 1997.

Uniprot ID: O00124

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 36 kDa

Calculated Molecular Weight: 64099 MW

Gene ID: 7993

Protein Name: UBX domain-containing protein 8

Gene Full Name: UBX domain protein 8

Synonyms: UBXN8; D8S2298E; REP8; UBXD6; UBX domain-containing protein 8; Reproduction 8 protein; Rep-8 protein; UBX domain-containing protein 6