Anti-SYNPO2L Antibody Picoband®

SKU: A14266-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SYNPO2L

Specificity:

Background: SYNPO2L belongs to the synaptopodin family and is an actin-associated protein that may play a role in modulating actin-based shape. SYNPO2L is involved in the positive regulation of Rho protein signal transduction and the positive regulation of stress fiber assembly. Loss-of-function variants in the SYNPO2L gene are associated with atrial fibrillation

Immunogen: E.coli-derived human SYNPO2L recombinant protein (Position: H66-E923). Human SYNPO2L shares 87.9% amino acid (aa) sequence identity with mouse SYNPO2L.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Lubitz, S. A., Brody, J. A., Bihlmeyer, N. A., Roselli, C., Weng, L. C., Christophersen, I. E., ... & Lin, H. (2016). Whole exome sequencing in atrial fibrillation. PLoS genetics, 12(9), e1006284. 2. Van Eldik, W., Den Adel, B., Monshouwer-Kloots, J., Salvatori, D., Maas, S., Van Der Made, I., ... & Beqqali, A. (2017). Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart. PLoS One, 12(12), e0189139. 3. Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., ... & Kääb, S. (2012). Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature genetics, 44(6), 670-675.

Uniprot ID: Q9H987

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 102 kDa

Calculated Molecular Weight: 102 kDa

Gene ID: 79933

Protein Name: Synaptopodin 2-like protein

Gene Full Name: synaptopodin 2 like

Synonyms: SYNPO2L; Synaptopodin 2-like protein