Anti-SMTN Antibody Picoband®

SKU: A04895-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SMTN

Specificity:

Background: Smoothelin is a protein that in humans is encoded by the SMTN gene. This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Immunogen: E.coli-derived human SMTN recombinant protein (Position: E72-D881).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Engelen, J. J. M., Esterling, L. E., Albrechts, J. C. M., Detera-Wadleigh, S. D., van Eys, G. J. J. M. Assignment of the human gene for smoothelin (SMTN) to chromosome 22q12 by fluorescence in situ hybridization and radiation hybrid mapping. Genomics 43: 245-247, 1997. 2. Rensen, S., Merkx, G., Doevendans, P., Geurts van Kessel, A., van Eys, G. Structure and chromosome location of Smtn, the mouse smoothelin gene. Cytogenet. Cell Genet. 89: 225-229, 2000. 3. van der Loop, F. T. L., Schaart, G., Timmer, E. D. J., Ramaekers, F. C. S., van Eys, G. J. J. M. Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells. J. Cell Biol. 134: 401-411, 1996.

Uniprot ID: P53814

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 120 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 6525

Protein Name: Smoothelin

Gene Full Name: smoothelin

Synonyms: smoothelin; SMSMO; SMTN