Anti-RUFY1 Antibody Picoband®

SKU: A10201-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RUFY1

Specificity:

Background: RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene. This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen: E.coli-derived human RUFY1 recombinant protein (Position: L20-Q650).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Yang, J., Kim, O., Wu, J., Qiu, Y. Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1: a possible role of ETK in regulation of vesicle trafficking. J. Biol. Chem. 277: 30219-30226, 2002.

Uniprot ID: Q96T51

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 80 kDa

Calculated Molecular Weight: 41409 MW

Gene ID: 80230

Protein Name: RUN and FYVE domain-containing protein 1

Gene Full Name: RUN and FYVE domain containing 1

Synonyms: FYVE finger protein EIP1; La binding protein 1; Rab4 interacting protein; RABIP4; RUFY1; ZFYVE12