Anti-RGL4 Antibody Picoband®

SKU: A16655-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RGL4

Specificity:

Background: This oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras-Raf-MEK-ERK cascade.

Immunogen: E.coli-derived human RGL4 recombinant protein (Position: R37-R381).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hernandez-Munoz, I., Benet, M., Calero, M., Jimenez, M., Diaz, R., Pellicer, A. rgr oncogene: activation by elimination of translational controls and mislocalization. Cancer Res. 63: 4188-4195, 2003. 2. Leonardi, P., Kassin, E., Hernandez-Munoz, I., Diaz, R., Inghirami, G., Pellicer, A. Human rgr: transforming activity and alteration in T-cell malignancies. Oncogene 21: 5108-5116, 2002.

Uniprot ID: Q8IZJ4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 52 kDa

Calculated Molecular Weight: 24145 MW

Gene ID: 266747

Protein Name: Ral-GDS-related protein

Gene Full Name: ral guanine nucleotide dissociation stimulator like 4

Synonyms: RGL4; RGR; Ral-GDS-related protein; hRGR; Ral guanine nucleotide dissociation stimulator-like 4; RalGDS-like 4