Anti-PTGER3 Antibody Picoband®

SKU: A02548-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PTGER3

Specificity:

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human PTGER3 recombinant protein (Position: K2-R390).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Adam, M., Boie, Y., Rushmore, T. H., Muller, G., Bastien, L., McKee, K. T., Metters, K. M., Abramovitz, M. Cloning and expression of three isoforms of the human EP(3) prostanoid receptor. FEBS Lett. 338: 170-174, 1994. 2. Aronoff, D. M., Lewis, C., Serezani, C. H., Eaton, K. A., Goel, D., Phipps, J. C., Peters-Golden, M., Mancuso, P. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J. Immun. 183: 2642-2649, 2009. 3. Duncan, A. M. V., Anderson, L. L., Funk, C. D., Abramovitz, M., Adam, M. Chromosomal localization of the human prostanoid receptor gene family. Genomics 25: 740-742, 1995.

Uniprot ID: P43115

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 48 kDa

Calculated Molecular Weight:

Gene ID: 5733

Protein Name: Prostaglandin E2 receptor EP3 subtype

Gene Full Name: prostaglandin E receptor 3

Synonyms: EP3; EP3 I; EP3 II; EP3 III; EP3 IV; EP3e; PGE receptor EP3 subtype; PGE2 R; PGE2 receptor EP3 subtype; Prostanoid EP3 receptor; PTGER3