Anti-PC4/SUB1 Antibody Picoband® (monoclonal, 6B5B10)

SKU: M02698-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat

Gene Name: SUB1

Specificity:

Background: Activated RNA polymerase II transcriptional coactivator p15, also known as positive cofactor 4 (PC4) or SUB1 homolog, is a protein that in humans is encoded by the SUB1 gene. This gene is mapped to 5p13.3. The transcriptional cofactor PC4 is an ancient single-strand DNA (ssDNA)-binding protein that has a homologue in bacteriophage T5 where it is likely the elusive replicative ssDNA-binding protein. The recombinant PC4 is shown to function identically to the native protein through its interaction with TAFs.

Immunogen: E.coli-derived human PC4/SUB1 recombinant protein (Position: N62-L127).

Clonality: Monoclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Entrez Gene SUB1: SUB1 homolog (S. cerevisiae). 2. Kretzschmar M, Kaiser K, Lottspeich F, Meisterernst M (August 1994). A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell 78 (3): 525–34. 3. Ge H, Roeder RG (August 1994). Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell 78 (3): 513–23.

Uniprot ID: P53999

Host: Mouse

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Mouse IgG2b

Phospho_site:

Clone Number: Clone: 6B5B10

Observed Molecular Weight: 18 kDa

Calculated Molecular Weight:

Gene ID: 10923

Protein Name: Activated RNA polymerase II transcriptional coactivator p15

Gene Full Name: SUB1 regulator of transcription

Synonyms: p14; PC4; Positive cofactor 4; RPO2TC1; SUB1; SUB1 homolog; SUB1 homolog (S. cerevisiae)