Anti-OSBPL5 Antibody Picoband®

SKU: A07477-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: OSBPL5

Specificity:

Background: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.

Immunogen: E.coli-derived human OSBPL5 recombinant protein (Position: R26-K879). Human OSBPL5 shares 84.4% amino acid (aa) sequence identity with mouse OSBPL5.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Chung, J., Torta, F., Masai, K., Lucast, L., Czapla, H., Tanner, L. B., Narayanaswamy, P., Wenk, M. R., Nakatsu, F., De Camilli, P. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts. Science 349: 428-432, 2015. 2. Higashimoto, K., Soejima, H., Yatsuki, H., Joh, K., Uchiyama, M., Obata, Y., Ono, R., Wang, Y., Xin, Z., Zhu, X., Masuko, S., Ishino, F., Hatada, I., Jinno, Y., Iwasaka, T., Katsuki, T., Mukai, T. Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse. Genomics 80: 575-584, 2002. Note: Erratum: Genomics 81, 346 only, 2003. 3. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001.

Uniprot ID: Q9H0X9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 99 kDa

Calculated Molecular Weight: 99 kDa

Gene ID: 114879

Protein Name: Oxysterol-binding protein-related protein 5

Gene Full Name: oxysterol binding protein like 5

Synonyms: OSBP related protein 5; ORP-5; ORP5; ORP 5; OBPH1