Anti-OPLAH Antibody Picoband®

SKU: A11695-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: OPLAH

Specificity:

Background: The protein encoded by this gene acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD).

Immunogen: E.coli-derived human OPLAH recombinant protein (Position: H788-E1072).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Almaghlouth, I. A., Mohamed, J. Y., Al-Amoudi, M., Al-Ahaidib, L., Al-Odaib, A., Alkuraya, F. S. 5-Oxoprolinase deficiency: report of the first human OPLAH mutation. Clin. Genet. 82: 193-196, 2012. 2. Calpena, E., Casado, M., Martinez-Rubio, D., Nascimento, A., Colomer, J., Gargallo, E., Garcia-Cazorla, A., Palau, F., Artuch, R., Espinos, C. 5-Oxoprolinuria in heterozygous patients for 5-oxoprolinase (OPLAH) missense changes. JIMD Rep. 7: 123-128, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 9/22/2011.

Uniprot ID: O14841

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 140 kDa

Calculated Molecular Weight:

Gene ID: 26873

Protein Name: 5-oxoprolinase

Gene Full Name: 5-oxoprolinase, ATP-hydrolysing

Synonyms: 5 Opase; 5 oxo L prolinase; 5 oxoprolinase; OPLA; OPLAH; Pyroglutamase