Anti-MICB Antibody Picoband®

SKU: PB9613

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: Flow Cytometry,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: MICB

Specificity: No cross reactivity with other proteins.

Background: MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MICB.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Bahram S, Bresnahan M, Geraghty DE, Spies T (Aug 1994). A second lineage of mammalian major histocompatibility complex class I genes. Proc Natl Acad Sci U S A 91 (14): 6259–63. 2. Entrez Gene: MICB MHC class I polypeptide-related sequence B. 3. Leelayuwat C, Townend DC, Degli-Esposti MA et al. (1994). A new polymorphic and multicopy MHC gene family related to nonmammalian class I..Immunogenetics 40 (5): 339–51.

Uniprot ID: Q29980

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60-65 kDa

Calculated Molecular Weight: 42646 MW

Gene ID: 4277

Protein Name: MHC class I polypeptide-related sequence B

Gene Full Name: MHC class I polypeptide-related sequence B

Synonyms: MIC B; MICB; PERB11.2