Anti-MARCO Antibody Picoband®

SKU: A00391-3

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: MARCO

Specificity:

Background: Macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene.

Immunogen: E.coli-derived human MARCO recombinant protein (Position: M1-R489). Human MARCO shares 66.5% amino acid (aa) sequence identity with mouse MARCO.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Arredouani, M., Yang, Z., Ning, Y. Y., Qin, G., Soininen, R., Tryggvason, K., Kobzik, L. The scavenger receptor MARCO is required for lung defense against Pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200: 267-272, 2004. 2. Dorrington, M. G., Roche, A. M., Chauvin, S. E., Tu, Z., Mossman, K. L., Weiser, J. N., Bowdish, D. M. E. MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J. Immun. 190: 250-258, 2013. 3. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I., Kraal, G., Tryggvason, K. Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80: 603-609, 1995.

Uniprot ID: Q9UEW3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 53 kDa

Calculated Molecular Weight: 53 kDa

Gene ID: 8685

Protein Name: Macrophage receptor MARCO

Gene Full Name: macrophage receptor with collagenous structure

Synonyms: MARCO; SCARA2; Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2