Anti-IFT172 Antibody Picoband®

SKU: A08217-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: IFT172

Specificity:

Background: This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10.

Immunogen: E.coli-derived human IFT172 recombinant protein (Position: D1505-Q1736). Human IFT172 shares 94.8% amino acid (aa) sequence identity with both mouse and rat IFT172.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bujakowska, K. M., Zhang, Q., Siemiatkowska, A. M., Liu, Q., Place, E., Falk, M. J., Consugar, M., Lancelot, M-E., Antonio, A., Lonjou, C., Carpentier, W., Mohand-Said, S., and 10 others. Mutations in IFT172 cause isolated retinal degeneration and Bardet-Biedl syndrome. Hum. Molec. Genet. 24: 230-242, 2015. 2. Casteels, I., Demandt, E., Legius, E. Visual loss as the presenting sign of Jeune syndrome. Europ. J. Paediat. Neurol. 4: 243-247, 2000. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/6/2014.

Uniprot ID: Q9UG01

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 180 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 26160

Protein Name: Intraflagellar transport protein 172 homolog

Gene Full Name: intraflagellar transport 172

Synonyms: DKFZp434A163; IFT172; KIAA1179; osm 1; SLB; wim