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GeneBio Systems

Anti-FUT4 Antibody Picoband®

Anti-FUT4 Antibody Picoband®

SKU:A04535-1

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Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.25-0.5μg/ml, Human

Gene Name: FUT4

Specificity:

Background: Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human FUT4, which shares 72.7% and 71.4% amino acid (aa) sequence identity with mouse and rat FUT4, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Cailleau-Thomas, A., Coullin, P., Candelier, J.-J., Balanzino, L., Mennesson, B., Oriol, R., Mollicone, R. FUT4 and FUT9 genes are expressed early in human embryogenesis. Glycobiology 10: 789-802, 2000. 2. Couillin, P., Mollicone, R., Grisard, M. C., Gibaud, A., Ravise, N., Feingold, J., Oriol, R. Chromosome 11q localization of one of the three expected genes for the human alpha-3-fucosyltransferases, by somatic hybridization. Cytogenet. Cell Genet. 56: 108-111, 1991. 3. Gersten, K. M., Natsuka, S., Trinchera, M., Petryniak, B., Kelly, R. J., Hiraiwa, N., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Lowe, J. B. Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase. J. Biol. Chem. 270: 25047-25056, 1995.

Uniprot ID: P22083

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 70 kDa

Calculated Molecular Weight:

Gene ID: 2526

Protein Name: Alpha-

Gene Full Name: fucosyltransferase 4

Synonyms: Alpha (1; 3) fucosyltransferase; ELFT; FCT3A; FUC TIV; Fucosyltransferase 4; Fucosyltransferase IV; FucT IV; FUT4; FUTIV

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