Anti-FMN1 Antibody Picoband®

SKU: A07520

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,WB

Application Details: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human,

Gene Name: FMN1

Specificity: No cross reactivity with other proteins.

Background: Formins, such as FMN1, are actin-nucleating proteins involved in cell polarity, cytokinesis, cell migration, and transcriptional activity. This FMN1 gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene.

Immunogen: E. coli-derived human FMN1 recombinant protein (Position: N1195-N1419). Human FMN1 shares 93.8% amino acid (aa) sequence identity with mouse FMN1.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Chalkia D, Nikolaidis N, Makalowski W, Klein J, Nei M (December 2008). Origins and evolution of the forminmultigene family that is involved in the formation of actin filaments. Molecular Biology and Evolution. 25 (12): 2717–33. 2. Evangelista M, Zigmond S, Boone C (July 2003). Formins: signaling effectors for assembly and polarization of actin filaments. Journal of Cell Science. 116 (Pt 13): 2603–11. 3. Goode BL, Eck MJ (2007). Mechanism and function of formins in the control of actin assembly. Annual Review of Biochemistry. 76: 593–627.

Uniprot ID: Q68DA7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 158 kDa

Calculated Molecular Weight: 157578 MW

Gene ID: 342184

Protein Name: Formin-1

Gene Full Name: formin 1

Synonyms: FMN; FMN1; FMN1 Ens; formin 1; LD