Anti-FAAH1/FAAH Antibody Picoband®

SKU: A00801-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: FAAH

Specificity:

Background: Fatty acid amide hydrolase or FAAH (EC 3.5.1.99, oleamide hydrolase, anandamide amidohydrolase) is a member of the serine hydrolase family of enzymes. This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide.

Immunogen: E.coli-derived human FAAH1/FAAH recombinant protein (Position: R34-S579).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Balsevich, G., Sticht, M., Bowles, N. P., Singh, A., Lee, T. T. Y., Li, Z., Chelikani, P. K., Lee, F. S., Borgland, S. L., Hillard, C. J., McEwen, B. S., Hill, M. N. Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. Proc. Nat. Acad. Sci. 115: 7605-7610, 2018. 2. Bracey, M. H., Hanson, M. A., Masuda, K. R., Stevens, R. C., Cravatt, B. F. Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling. Science 298: 1793-1796, 2002. 3. Chiang, K. P., Gerber, A. L., Sipe, J. C., Cravatt, B. F. Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use. Hum. Molec. Genet. 13: 2113-2119, 2004.

Uniprot ID: O00519

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 63 kDa

Calculated Molecular Weight: 51512 MW

Gene ID: 2166

Protein Name: Fatty-acid amide hydrolase 1

Gene Full Name: fatty acid amide hydrolase

Synonyms: Anandamide amidohydrolase 1; FAAH; FAAH 1; FAAH1; fatty acid amide hydrolase; Fatty acid amide hydrolase 1; Oleamide hydrolase 1