Anti-ETS1 Antibody Picoband®

SKU: A00931-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,IP

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse
Immunoprecipitation, 0.5-2 μg/ml, Human

Gene Name: ETS1

Specificity: No cross reactivity with other proteins.

Background: Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. It is mapped to 11q24.3. This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ETS1, identical to the related mouse and rat sequences.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G (Sep 1992). Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature. 359 (6391): 162–5. 2. Dwyer J, Li H, Xu D, Liu JP (Oct 2007). Transcriptional regulation of telomerase activity: roles of the Ets transcription factor family. Annals of the New York Academy of Sciences. 1114 (1): 36–47.

Uniprot ID: P14921

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 50 kDa

Calculated Molecular Weight: 50 kDa

Gene ID: 2113

Protein Name: Protein C-ets-1

Gene Full Name: ETS proto-oncogene 1, transcription factor

Synonyms: ETS 1; ETS1; EWSR2; p54; Protein C ets 1