Anti-Cullin 5/CUL5 Antibody Picoband®

SKU: A01925-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,WB

Application Details: Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Gene Name: CUL5

Specificity: No cross reactivity with other proteins.

Background: Cullin-5 is a protein that in humans is encoded by the CUL5 gene. Cul5 inhibits cellular proliferation, potentially through its involvement in the SOCS/ BC-box/ eloBC/ cul5/ RING E3 ligase complex, which functions as part of the ubiquitin system for protein degradation. One study have shown that Cul5 plays a role in Reelin signaling cascade, participating in the DAB1 degradation and thus ensuring the negative feedback mechanism of Reelin signaling during corticogenesis.

Immunogen: E. coli-derived human Cullin 5 recombinant protein (Position: A2-D105).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Feng L, Allen NS, Simo S, Cooper JA (November 2007). Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development. Genes Dev. 21 (21): 2717–30. 2. Petroski MD, Deshaies RJ (2005). Function and regulation of cullin-RING E3 ligases. Nature Reviews Molecular Cell Biology. 6 (1): 9–21.

Uniprot ID: Q93034

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 91 kDa

Calculated Molecular Weight:

Gene ID: 8065

Protein Name: Cullin-5

Gene Full Name: cullin 5

Synonyms: Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1; CUL5; VACM1