Anti-CRABP2 Antibody Picoband®

SKU: A03297-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: CRABP2

Specificity:

Background: Cellular retinoic acid-binding protein 2 is a cytoplasmic binding protein that in humans is encoded by the CRABP2 gene. This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Immunogen: E.coli-derived human CRABP2 recombinant protein (Position: R60-D117).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Elder, J. T., Astrom, A., Pettersson, U., Voorhees, J. J., Trent, J. M. Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization. Hum. Genet. 89: 487-490, 1992. 2. Flagiello, D., Apiou, F., Gibaud, A., Poupon, M. F., Dutrillaux, B., Malfoy, B. Assignment of the genes for cellular retinoic acid binding protein 1 (CRABP1) and 2 (CRABP2) to human chromosome band 15q24 and 1q21.3, respectively, by in situ hybridization. Cytogenet. Cell Genet. 76: 17-18, 1997. 3. Giguere, V., Lyn, S., Yip, P., Siu, C.-H., Amin, S. Molecular cloning of cDNA encoding a second cellular retinoic acid-binding protein. Proc. Nat. Acad. Sci. 87: 6233-6237, 1990.

Uniprot ID: P29373

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 17 kDa

Calculated Molecular Weight:

Gene ID: 1382

Protein Name: Cellular retinoic acid-binding protein 2

Gene Full Name: cellular retinoic acid binding protein 2

Synonyms: CRABP II; CRABP2; RBP6