Anti-ARL2 Antibody Picoband®

SKU: A04155-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: ARL2

Specificity:

Background: ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene. This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ARL2, which shares 90.9% amino acid (aa) sequence identity with mouse and rat ARL2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bowzard, J. B., Cheng, D., Peng, J., Kahn, R. A. ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs. J. Biol. Chem. 282: 17568-17580, 2007. 2. Cai, X.-B., Wu, K.-C., Zhang, X., Lv, J.-N., Jin, G.-H., Xiang, L., Chen, J., Huang, X.-F., Pan, D., Lu, B., Lu, F., Qu, J., Jin, Z.-B. Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome. Clin. Genet. 96: 61-71, 2019. 3. Clark, J., Moore, L., Krasinskas, A., Way, J., Battey, J., Tamkun, J., Kahn, R. A. Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes. Proc. Nat. Acad. Sci. 90: 8952-8956, 1993.

Uniprot ID: P36404

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 18 kDa

Calculated Molecular Weight: 21 kDa

Gene ID: 402

Protein Name: ADP-ribosylation factor-like protein 2

Gene Full Name: ARF like GTPase 2

Synonyms: ADP ribosylation factor like 2; ARFL2; ARL2