Anti-Amyloid-like protein 2 APLP2 Antibody Picoband®

SKU: PA1654-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Gene Name: APLP2

Specificity: No cross reactivity with other proteins.

Background: APLP2 (Amyloid beta (A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human APLP2, different from the related rat and mouse sequences by one amino acid.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Leach, R., Ko, M., Krawetz, S. A. Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization. Cytogenet. Cell Genet. 87: 215-216, 1999. 2. von der Kammer, H., Loffler, C., Hanes, J., Klaudiny, J., Scheit, K. H., Hansmann, I. The gene for the amyloid precursor-like protein APLP2 is assigned to human chromosome 11q23-25. Genomics 10: 308-311, 1994. 3. Leach R, Ko M, Krawetz SA (1999). Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization. Cytogenet. Cell Genet. 87 (3–4): 215–6.

Uniprot ID: Q06481

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 100-110 kDa

Calculated Molecular Weight: 86956 MW

Gene ID: 334

Protein Name: Amyloid beta precursor like protein 2

Gene Full Name: amyloid beta precursor like protein 2

Synonyms: Amyloid like protein 2; Amyloid protein homolog; APLP 2; APLP2; APPH; APPL2; CDEBP; CDEI box binding protein