ANK3 Antibody - Cat. #: CSB-PA981926

SKU: CSB-PA981926

Size :50ul

Clone Number:

Aliases:ANK-3 antibody; ANK3 antibody; ANK3_HUMAN antibody; ankyrin 3 (G) antibody; Ankyrin 3; node of Ranvier (ankyrin G) antibody; Ankyrin 3; node of Ranvier antibody; Ankyrin G antibody; Ankyrin G119 antibody; Ankyrin-3 antibody; Ankyrin-G antibody; brain specific ankyrin G antibody; CHANK3 antibody; FLJ45464 antibody; OTTHUMP00000217458 antibody; OTTHUMP00000217575 antibody; RP11 369L1.1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q12955

Immunogen:Synthetic peptide of Human ANK3

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ANK3

Research Areas:Neuroscience