AlaRS antibody , Cat. # FNab00276

SKU: FNab00276

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:AARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1, cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs(PMID:19661429).

Immunogen:alanyl-tRNA synthetase

Synonyms:AARS, Alanine tRNA ligase, alanyl tRNA synthetase, AlaRS

Observed MW:107 kDa

Uniprot ID:P49588

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF, IP

Recommended dilution:WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000

Gene ID:

Research Area:Neuroscience, Metabolism