AKR1C1 Polyclonal Antibody

SKU: E-AB-12710

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: AKR1C1

Target Synonym: 2-dihydrobenzene-1;2-diol dehydrogenase;20 alpha (3 alpha) hydroxysteroid dehydrogenase;20 ALPHA HSD;20 alpha hydroxysteroid dehydrogenase;20-alpha-HSD;20-alpha-hydroxysteroid dehydrogenase;20ALPHAHSD;2ALPHAHSD;AK1C1;AK1C1;AKR1C1;Aldo keto reductase family 1 member C1;aldo-keto reductase C;Aldo-keto reductase family 1 member C1;Aldo-keto reductase family;1 member 1;C9;Chlordecone reductase homolog;Chlordecone reductase homolog HAKRC;DD1;DD1/DD2;DDH;DDH1;Dihydrodiol dehydrogenase 1;Dihydrodiol dehydrogenase 1/2;dihydrodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase;dihydrodiol dehydrogenase isoform DD1;Dihydrodiol dehydrogenase;type 1;H37;HAKRC;HBAB;Hepatic dihydrodiol dehydrogenase;High affinity hepatic bile acid-binding protein;High-affinity hepatic bile acid-binding protein;Indanol dehydrogenase;MBAB;MGC8954;Trans-1;Trans-1;2 dihydrobenzene 1;2 diol dehydrogenase;Type II 3 alpha hydroxysteroid dehydrogenase

Research Areas: Metabolism;Developmental Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q04828

Accession:

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human AKR1C1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 37kDa

ObservedMW: