AHA-1 rabbit pAb

SKU: ES1612

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300;ELISA 1:5000-20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):38kD

Human_gene_id:10598

Human_swiss_prot_no:O95433

Subcellular_location:Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.

Other_name:AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38

Background:function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,