AGXT Polyclonal Antibody

SKU: E-AB-12706

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:AGXT

Target Synonym:AGT;AGT1;Agxt;AGXT1;Alanine glyoxylate aminotransferase;Alanine glyoxylate aminotransferase3;Alanine--glyoxylate aminotransferase;EC 2.6.1.44;EC 2.6.1.51;Hepatic peroxisomal alanine glyoxylate aminotransferase;Hepatic peroxisomal alanine:glyoxylate aminotransferase;L alanine glyoxylate aminotransferase 1;MS773;PH1;Serine pyruvate aminotransferase;Serine--pyruvate aminotransferase;Serine--pyruvate aminotransferase;mitochondrial;Serine:pyruvate aminotransferase;SPAT;SPT;SPYA;TLH6

Research Areas:Cancer;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P21549

Accession:

Background:Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Concentration:0.6 mg/mL

Immunogen:Synthetic peptide of human AGXT

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:43kDa

ObservedMW: