AF/LE Purified Anti-Mouse CD209b Antibody[22D1]

SKU: GBS-F10220

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD209b

Target Synonym:CD209;CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7

Research Areas:无

Conjugation:None (AF/LE)

Host:Armenian Hamster

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Armenian Hamster IgG

Clonality:Monoclonal

Clone NO.:22D1

UNIProt ID:Q8CJ91

Background:CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:

Dilution:

GeneID: