ACVR2A Antibody - Cat. #: CSB-PA110386

SKU: CSB-PA110386

Size :50ul

Clone Number:

Aliases:Activin A receptor type IIA antibody; Activin receptor type 2A antibody; Activin receptor type IIA antibody; Activin receptor type-2A antibody; ACTR 2 antibody; ACTR IIA antibody; ACTR-IIA antibody; ACTR2 antibody; ACTRII antibody; ACTRIIA antibody; Acvr 2 antibody; Acvr 2A antibody; Acvr2 antibody; ACVR2A antibody; AVR2A_HUMAN antibody; OTTHUMP00000197918 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P27037

Immunogen:Fusion protein of Human ACVR2A

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ACVR2A

Research Areas:Cancer;Metabolism;Signal transduction?Stem cells