ACTN1 Monoclonal Antibody

SKU: E-AB-22127

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: ACTN1

Target Synonym: actinin 1 smooth muscle;Actinin alpha 1;actinin;alpha 1;ACTN 1;Actn1;ACTN1;Alpha Actinin 1;Alpha actinin cytoskeletal isoform;Alpha-actinin cytoskeletal isoform;Alpha-actinin-1;BDPLT15;F actin cross linking protein;F-actin cross-linking protein;FLJ40884;FLJ54432;Non muscle alpha actinin 1;Non-muscle alpha-actinin-1

Research Areas: Cancer;Developmental Biology;Signal Transduction;Stem Cells

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human;Mouse;Rat

Application: IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:1D4

UNIProt ID: P12814

Accession:

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein of a-actinin of ACTN1

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Protein A purification

Dilution: IHC 1:100-200

Calculated MW:

ObservedMW: