ACMSD Polyclonal Antibody

SKU: E-AB-10712

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ACMSD

Target Synonym: 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase;2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;acmsd;ACMSD;Aminocarboxymuconate semialdehyde decarboxylase;Picolinate carboxylase

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q8TDX5

Accession:

Background: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human ACMSD

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 38kDa

ObservedMW: