ZNF281 Antibody, HRP conjugated - Cat. #: CSB-PA026637LB01HU

SKU: CSB-PA026637LB01HU

Size :50ug

Clone Number:

Aliases:GC box binding zinc finger protein 1 antibody; GC-box-binding zinc finger protein 1 antibody; GZP1 antibody; Transcription factor ZBP-99 antibody; ZBP 99 antibody; ZBP99 antibody; zfp281 antibody; Zinc finger DNA binding protein 99 antibody; Zinc finger DNA-binding protein 99 antibody; Zinc finger protein 281 antibody; ZN281_HUMAN antibody; ZNF281 antibody; ZNP 99 antibody; ZNP 99 transcription factor antibody; ZNP99 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y2X9

Immunogen:Recombinant Human Zinc finger protein 281 protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ZNF281

Research Areas:Epigenetics and Nuclear Signaling; Developmental biology; Stem cells