ZIC1 Antibody - Cat. #: CSB-PA795975

SKU: CSB-PA795975

Size :100ul

Clone Number:

Aliases:Odd paired homolog Drosophila antibody; Zic 1 antibody; ZIC antibody; Zic family member 1 (odd-paired Drosophila homolog) antibody; Zic family member 1 antibody; Zic protein member 1 antibody; zic1 antibody; ZIC1_HUMAN antibody; Zinc finger protein 201 antibody; Zinc finger protein of the cerebellum 1 antibody; Zinc finger protein ZIC 1 antibody; Zinc finger protein ZIC1 antibody; ZNF 201 antibody; ZNF201 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15915

Immunogen:Synthesized peptide derived from internal of Human ZIC1/2/3.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.

Yokota N., Cancer Res. 56:377-383(1996).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ZIC1

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience;Signal transduction