ZBTB16 Monoclonal Antibody

SKU: BT-MCA3212

Size:100μL

Background:This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Research_area:Stem cells, Cancer, Epigenetics and nuclear signaling, Developmental biology

Target_protein:ZBTB16

applications:WB, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:5B3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ZBTB16

Immunogen:Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):74kDa

UniProt accession:Q05516

Synonyms:PLZF, ZNF145, ZBTB16

GeneID:7704