YTHDF1 antibody , Cat. # FNab09572

SKU: FNab09572

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).

Immunogen:YTH domain family, member 1

Synonyms:C20orf21, DACA 1, FLJ20391, YTH domain family protein 1, YTH domain family, member 1, YTHDF1

Observed MW:62 kDa

Uniprot ID:Q9BYJ9

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP

Recommended dilution:WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200

Gene ID:54915

Research Area:Signal Transduction