XPG antibody , Cat. # FNab09547

SKU: FNab09547

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair(NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].

Immunogen:excision repair cross-complementing rodent repair deficiency, complementation group 5

Synonyms:COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC

Observed MW:200 kDa

Uniprot ID:P28715

Reactivity:Human

Tested Application:ELISA, WB, IP

Recommended dilution:WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000

Gene ID:

Research Area:Epigenetics, Metabolism