XPA Antibody - Cat. #: CSB-PA238469

SKU: CSB-PA238469

Size :100ul

Clone Number:

Aliases:DNA repair protein complementing XP A cells antibody; DNA repair protein complementing XP-A cells antibody; DNA repair protein complementing XPA cells antibody; Excision repair controlling antibody; Xeroderma pigmentosum 1 antibody; Xeroderma pigmentosum complementation group A antibody; Xeroderma pigmentosum group A complementing protein antibody; Xeroderma pigmentosum group A-complementing protein antibody; XP 1 antibody; XP1 antibody; xpa antibody; XPA_HUMAN antibody; Xpac antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P23025

Immunogen:Synthesized peptide derived from Internal of Human XPA.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.

Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183.
Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619.
Karen M. Vasquez, PNAS, Apr 2002; 99: 5848.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:XPA

Research Areas:Epigenetics and Nuclear Signaling