WDFY2 Antibody - Cat. #: CSB-PA850405LA01HU

SKU: CSB-PA850405LA01HU

Size :50ug

Clone Number:

Aliases:PROF antibody; Propeller-FYVE protein antibody; RP11 147H23.1 antibody; WD repeat and FYVE domain containing 2 antibody; WD repeat and FYVE domain-containing protein 2 antibody; WD40 and FYVE domain containing 2 antibody; WD40- and FYVE domain-containing protein 2 antibody; WDF2 antibody; Wdfy2 antibody; WDFY2_HUMAN antibody; ZFYVE22 antibody; Zinc finger FYVE domain-containing protein 22 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96P53

Immunogen:Recombinant Human WD repeat and FYVE domain-containing protein 2 protein (2-114AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background:Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WDFY2

Research Areas:Signal transduction