WAS Antibody - Cat. #: CSB-PA785437

SKU: CSB-PA785437

Size :100ul

Clone Number:

Aliases:Eczema thrombocytopenia antibody; IMD2 antibody; SCNX antibody; THC antibody; THC1 antibody; Thrombocytopenia 1 (X linked) antibody; U42471 antibody; Was antibody; WASp antibody; WASP_HUMAN antibody; Wiskott Aldrich syndrome (eczema thrombocytopenia) antibody; Wiskott Aldrich syndrome antibody; Wiskott Aldrich syndrome protein antibody; Wiskott-Aldrich syndrome protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P42768

Immunogen:Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.

Kolluri R., Tolias K.F., Carpenter C.L., Rosen F.S. Proc. Natl. Acad. Sci. U.S.A. 93:5615-5618(1996)
Ramesh N., Anton I.M., Hartwig J.H., Geha R.S. Proc. Natl. Acad. Sci. U.S.A. 94:14671-14676(1997)
Cory G.O.C., Cramer R., Blanchoin L., Ridley A.J. Mol. Cell 11:1229-1239(2003)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WAS

Research Areas:Signal transduction